• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human IL-29 protein

Activity(Primary)

0.12-0.6 ng/mL EC50

Specific Activity

>8.00 x 105 IU/mg

Species Reactivity

human

Purity

>95%

Cat no : HZ-1156

Synonyms

Cytokine Zcyto21, IFN lambda 1, IFNL1, IFN-lambda 1, IL 29, IL29, IL-29, Interferon lambda 1, Interleukin 29, ZCYTO21



Technical Specifications

GeneID 282618
Species Human
Expression HEK293
Activity(Primary) 0.12-0.6 ng/mL EC50
Specific Activity>8.00 x 105 IU/mg
Purity >95%
Endotoxin<1 EU/μg
Accession NumberQ8IU54
Molecular Mass 27 and 31 kDa reduced, 25 and 30 kDa non-reduced, monomer, glycosylated
Formulation 1x PBS, See Certificate of Analysis for details
Species Reactivity human

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Background

Interleukin-29(IL-29, also known as IFN gamma1)is a member of the helical cytokine family and is a type III interferon. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses (PMID: 18547367;12469119;27637354)

Synonyms

Cytokine Zcyto21, IFN lambda 1, IFNL1, IFN-lambda 1, IL 29, IL29, IL-29, Interferon lambda 1, Interleukin 29, ZCYTO21

Publications

SpeciesTitle

Int J Mol Sci

Multifaceted Analysis of IL-23A- and/or EBI3-Including Cytokines Produced by Psoriatic Keratinocytes.

Authors - Kota Tachibana

Antiviral Res

Antiviral candidates against the hepatitis E virus (HEV) and their combinations inhibit HEV growth in in vitro.

Authors - Takashi Nishiyama
human

Cell Rep

Critical role of Syk-dependent STAT1 activation in innate antiviral immunity.

Authors - Shasha Liu
human

J Virol Methods

Screening of novel drugs for inhibiting hepatitis E virus replication.

Authors - Takashi Nishiyama