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  • KD/KO Validated

SULT4A1 Polyclonal antibody

SULT4A1 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IP, IF, IHC, ELISA

Conjugate

Unconjugated

Cat no : 12578-1-AP

Synonyms

BR STL 1, BRSTL1, hBR STL, hBR STL 1, NST, ST4A1, Sulfotransferase 4A1, SULT4A1, SULTX3



Tested Applications

Positive WB detected inmouse brain tissue, human brain tissue, rat brain
Positive IP detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

12578-1-AP targets SULT4A1 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, zebrafish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SULT4A1 fusion protein Ag3271
Full Name sulfotransferase family 4A, member 1
Calculated Molecular Weight 284 aa, 33 kDa
Observed Molecular Weight 30-33 kDa
GenBank Accession NumberBC022459
Gene Symbol SULT4A1
Gene ID (NCBI) 25830
RRIDAB_2197933
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SULT4A1, also named as SULTX3, NST, ST4A1, hBR-STL and hBR-STL-1, belongs to the sulfotransferase 1 family. It may catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. SULT4A1 displays activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphtylamine, and 2-naphtol. It may have a role in the sulfation of drugs and neurotransmitters in the CNS. SULT4A1 is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. It is a novel cytosolic sulfotransferase that is primarily expressed in the brain.

Protocols

Product Specific Protocols
WB protocol for SULT4A1 antibody 12578-1-APDownload protocol
IP protocol for SULT4A1 antibody 12578-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse,ratWB,IF

J Neurosci

SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex.

Authors - Lorenza Culotta
  • KD Validated
human,ratWB,IHC

Biochem Pharmacol

Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells.

Authors - Shu Xiao-Hong XH
mouseWB

Mol Pharmacol

Regulation of mouse brain-selective sulfotransferase sult4a1 by cAMP response element-binding protein and activating transcription factor-2.

Authors - Butcher Neville J NJ
humanWB

FEBS J

Distinct sulfonation activities in resveratrol-sensitive and resveratrol-insensitive human glioblastoma cells.

Authors - Sun Zheng Z
WB

Sci Rep

Sulfotransferase 4A1 activity facilitates sulfate-dependent cellular protection to oxidative stress.

Authors - Evan J Brettrager
humanWB,IHC,IF

PLoS One

Metabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficacies.

Authors - Shu Xiao-Hong XH