SOHLH1 Polyclonal antibody

SOHLH1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF, IHC, ELISA

Conjugate

Unconjugated

Cat no : 17753-1-AP

Synonyms

C9orf157, NOHLH, SOHLH1, TEB2



Tested Applications

Positive IHC detected inhuman testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17753-1-AP targets SOHLH1 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SOHLH1 fusion protein Ag12107
Full Name spermatogenesis and oogenesis specific basic helix-loop-helix 1
Calculated Molecular Weight 328 aa, 34 kDa
GenBank Accession NumberBC031861
Gene Symbol SOHLH1
Gene ID (NCBI) 402381
RRIDAB_2878434
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Spermatogenesis‐and oogenesis‐specific helix‐loop‐helix transcription factor 1 (SOHLH1) is a gonad‐specific transcription factor that belongs to the basic‐helix‐loop‐helix (bHLH) transcription factor family. SOHLH1 has a profound effect on the development of germ cells, from SSC self-maintenance to spermatogonium differentiation.

Protocols

Product Specific Protocols
IHC protocol for SOHLH1 antibody 17753-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB, IF

Hum Mol Genet

The mutation c.346-1G > a in SOHLH1 impairs sperm production in the homozygous but not in the heterozygous condition.

Authors - Mohan Liu