RETNLB Polyclonal antibody

RETNLB Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 18232-1-AP

Synonyms

CCRG, FIZZ1, FIZZ2, HXCP2, RELM beta, RELMb, RELMbeta, resistin like beta, RETNL2, RETNLB, XCP2

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Validation Data Gallery

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  IHC staining of human small intestine using 18232-1-AP

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 18232-1-AP (RETNLB antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human small intestine using 18232-1-AP

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 18232-1-AP (RETNLB antibody) at dilution of 1:200 (under 40x lens).

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Tested Applications

• Positive IHC detected in: human small intestine tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

18232-1-AP targets RETNLB in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: RETNLB fusion protein Ag12912
• Full Name: resistin like beta
• Calculated Molecular Weight: 111 aa, 12 kDa
• GenBank Accession Number: BC069318
• Gene Symbol: RETNLB
• Gene ID (NCBI): 84666
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

RETNLB is an intestinal goblet cell-specific protein and is notably upregulated during intestinal inflammation. RETNLB also plays a role in several research areas, such as inflammatory disease, cancer, and metabolic function. In tumors, previous reports have suggested that positive expression of RETNLB was detected in most tissues from gastric carcinoma and colon cancer patients, RETNLB was also found involvement in oral squamous cell carcinoma [PMID: 34158059 19706296 27001185 15983036].