MAP17 / PDZK1IP1 Polyclonal antibody

MAP17 / PDZK1IP1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 12518-1-AP

Synonyms

DD96, MAP17, PDZK1 interacting protein 1, PDZK1IP1, Protein DD96, RP1 18D14.5, SPAP

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Validation Data Gallery

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  IHC staining of human kidney using 12518-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 12518-1-AP (MAP17 / PDZK1IP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human kidney using 12518-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 12518-1-AP (MAP17 / PDZK1IP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Tested Applications

• Positive IHC detected in: human kidney tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

12518-1-AP targets MAP17 / PDZK1IP1 in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MAP17 / PDZK1IP1 fusion protein Ag3206
• Full Name: PDZK1 interacting protein 1
• Calculated Molecular Weight: 114 aa, 12 kDa
• GenBank Accession Number: BC012303
• Gene Symbol: PDZK1IP1
• Gene ID (NCBI): 10158
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

PDZK1-interacting protein 1(PDZK1IP1), also known as MAP17, is a membrane-associated protein. MAP17 / PDZK1IP1 is overexpressed in a variety of human carcinomas, and overexpression of MAP17 / PDZK1IP1 protein is strongly correlated with the progression of prostate and ovarian carcinomas (PMID: 17426052). MAP17 / PDZK1IP1 has been proven to be an oncogene for tumorigenesis and development of papillary thyroid cancer (PTC) (PMID: 36057192; PMID: 35727731).