neuron navigator 1 Polyclonal antibody

neuron navigator 1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 20807-1-AP

Synonyms

KIAA1151, KIAA1213, NAV1, neuron navigator 1, POMFIL3, steerin 1, STEERIN1, Unc 53 homolog 1, unc53H1

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Validation Data Gallery

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  IHC staining of human heart using 20807-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 20807-1-AP (neuron navigator 1 antibody at dilution of 1:200 (under 10x lens).

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  IHC staining of human heart using 20807-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 20807-1-AP (neuron navigator 1 antibody at dilution of 1:200 (under 40x lens).

• 

  IHC staining of human skeletal muscle using 20807-1-AP

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 20807-1-AP (neuron navigator 1 antibody at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human placenta using 20807-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 20807-1-AP (neuron navigator 1 antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human placenta using 20807-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 20807-1-AP (neuron navigator 1 antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human skeletal muscle using 20807-1-AP

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 20807-1-AP (neuron navigator 1 antibody at dilution of 1:200 (under 40x lens).

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Tested Applications

• Positive IHC detected in: human heart tissue, human placenta tissue, human skeletal muscle tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 20807-1-AP is neuron navigator 1 Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: neuron navigator 1 fusion protein Ag14747
• Full Name: neuron navigator 1
• Calculated Molecular Weight: 1877 aa, 202 kDa
• GenBank Accession Number: BC007523
• Gene Symbol: NAV1
• Gene ID (NCBI): 89796
• RRID: AB_10732685
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Neuron navigator 1 (NAV1) gene encodes a large protein belongs to the Nav/unc-53 family and 7 isoforms of NAV1 are produced by alternative splicing. NAV1 is localized in cytoplasm and expressed at high levels in heart, skeletal muscle and placenta, and especially in neuronal growth cones. Besides its nucleotide binding activity, NAV1 interacts with tubulin and associates with a subset of microtubule plus end, therefore playing a role in neuronal migration.