MYO1E Monoclonal antibody, PBS Only

MYO1E Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A12F5

Cat no : 68152-1-PBS

Synonyms

HuncM IC, MYO1E, Myosin Ic, myosin IE

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Validation Data Gallery

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  WB analysis using 68152-1-Ig (same clone as 68152-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68152-1-Ig (MYO1E antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68152-1-PBS in a different storage buffer formulation.

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Recommended dilution

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68152-1-PBS targets MYO1E in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

• Tested Reactivity: Human, Mouse, Rat
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: MYO1E fusion protein Ag12244
• Full Name: myosin IE
• Calculated Molecular Weight: 1108 aa, 127 kDa
• Observed Molecular Weight: 120-150 kDa
• GenBank Accession Number: BC098392
• Gene Symbol: MYO1E
• Gene ID (NCBI): 4643
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

MYO1E, also named as Myosin-Ie and MYO1C (distinct from the MYO1C gene located on chromosome 17), encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6.