MBOAT7 Polyclonal antibody

MBOAT7 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 26646-1-AP

Synonyms

BB1, h mboa 7, hMBOA 7, LENG4, LPIAT, LPLAT 7, LRC4, Lyso PI acyltransferase, Lysophospholipid acyltransferase 7, MBOA7, MBOAT7, OACT7

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Validation Data Gallery

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  WB analysis using 26646-1-AP

  mouse liver tissue was subjected to SDS PAGE followed by western blot with 26646-1-AP (MBOAT7 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse liver tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

26646-1-AP targets MBOAT7 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MBOAT7 fusion protein Ag24490
• Full Name: membrane bound O-acyltransferase domain containing 7
• Calculated Molecular Weight: 472 aa, 53 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC006309
• Gene Symbol: MBOAT7
• Gene ID (NCBI): 79143
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

MBOAT7 (membrane-bound O-acyltransferase domain containing 7), also known as LPIAT1, LENG4, or BB1, belongs to the MBOAT superfamily. MBOAT7 acylates lyso-phosphatidylinositol (lyso-PI) with arachidonyl-CoA and is involved in phosphatidylinositol acyl-chain remodeling in the Lands cycle (PMID: 30959108; PMID: 35509994). MBOAT7 deficiency in humans leads to developmental disorders of the central nervous system, with intellectual disability, epilepsy, and autism spectrum disorder (PMID: 37316513). The calculated molecular weight of MBOAT7 is 53 kDa. This antibody can recognize the 45 kDa isoform of MBOAT7.