IL-1RAP Polyclonal antibody
IL-1RAP Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, Mouse
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 30966-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HeLa cells, human placenta tissue, mouse liver tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:3000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
30966-1-AP targets IL-1RAP in WB, ELISA applications and shows reactivity with Human, Mouse samples.
Tested Reactivity | Human, Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | IL-1RAP fusion protein Ag34121 |
Full Name | interleukin 1 receptor accessory protein |
Calculated Molecular Weight | 65 kDa |
Observed Molecular Weight | 70 kDa |
GenBank Accession Number | NM_001167928.1 |
Gene Symbol | IL1RAP |
Gene ID (NCBI) | 3556 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity Purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
IL-1RAP (Interleukin-1 receptor accessory protein), also known as IL-1RAcP, IL-1R-3, or IL-1R3, is a member of the interleukin-1 receptor family. IL-1RAP is composed of an extracellular region containing three Ig-like C2 type domains, a transmembrane region, and a cytoplasmic region with a TIR (Toll-IL-1-receptor) domain. IL-1RAP functions as a co-receptor for IL-1, IL-33, IL-36. It plays an essential role in the signaling of the IL-1 family cytokines such as IL-1, IL-33, and IL-36, as well as tyrosine kinases FLT3 and c-Kit. IL-1RAP can also exist in a soluble form.
Protocols
Product Specific Protocols | |
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WB protocol for IL-1RAP antibody 30966-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |