FYTTD1 Polyclonal antibody

FYTTD1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 24560-1-AP

Synonyms

FYTTD1, Protein 40 2 3, UAP56 interacting factor, UIF

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Validation Data Gallery

• 

  WB analysis of HeLa using 24560-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 24560-1-AP (FYTTD1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HeLa cells

Recommended dilution

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 24560-1-AP is FYTTD1 Fusion Protein expressed in E. coli.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FYTTD1 fusion protein Ag20051
• Full Name: forty-two-three domain containing 1
• Calculated Molecular Weight: 318 aa, 36 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC039734
• Gene Symbol: FYTTD1
• Gene ID (NCBI): 84248
• RRID: AB_2879609
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FYTTD1 also termed as UAP56 interacting factor or UIF is a 318 amino acid protein, which belongs to the UIF family. FYTTD1 localizes to nucleus and is required for mRNA export from nucleus to cytoplasm. Functioning as an adaptor, FYTTD1 utilizes the BAT1/DDX39-TAP pathway, which is essential for efficient mRNA export and nuclear pore delivery. FYTTD1 interacts with SSRP1, a protein that is necessary for its recruitment of mRNAs, in addition to a mutually exclusive interaction with BAT1/DDX39 and TAP. The molecular weight of post-translation modified FYTTD1 is observed 50 kDa.