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  • p38 mapk signaling pathway
Activation Inhibition Indirectly activation Translocation Phosphorylation P mRNA Stability Stress Conditions Translationof mRNAs TGF-βReceptor RTK GPCR CytokineReceptor DAXX TAB1 p38 MAPK p38 MAPK MAPKAPK2 MAPKAPK2 TTP HSP27 CDC25 PRAK DUSP1 DUSP1 SHC GRB2 SOS CDC42 TRAF2 TRAF6 IRAK TRADD MLK2/3 TAK1 DLK ASK1/2 TAO1/2 MAP2K4 MAP2K3 MAP3K1-4 MAP2K6 JUN p53 CHOP MEF2 Tau EEF2K RIP CREB ATF1 Histone H3 c-MYC ELK STAT Gβ Gγ Gα MNK1/2 EIF4G EIF4E EIF4A EIF3 RAS RAC RAS GTP GTP GDP GDP P P P P P P P P P P P P P P P P P Cytoplasm Nucleus MSK

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