SORCS1 Polyclonal antibody
SORCS1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 18839-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | Y79 cells, HEK-293 cells, mouse brain tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
18839-1-AP targets SORCS1 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide |
Full Name | sortilin-related VPS10 domain containing receptor 1 |
Calculated Molecular Weight | 1168 aa, 130 kDa |
Observed Molecular Weight | 130 kDa, 60-80 kDa |
GenBank Accession Number | BC131597 |
Gene Symbol | SORCS1 |
Gene ID (NCBI) | 114815 |
RRID | AB_2878564 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
SorCS1 is a 130 kDa type I transmembrane protein, belonging to Vps10p-domain (Vps10p-D) receptor family that comprises an N-terminal Vps10p-D, a leucine-rich domain, a single transmembrane domain, and a short cytoplasmic domain. SorCS1 is synthesized as a proprotein, which is converted to the mature receptor in late Golgi compartments by cleavage of the N-terminal propeptide. Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic domains and differential expression in tissues. This antibody was generated against the C-terminal region of human SorCS1 and recognizes various forms of SorCS1. Multiple bands around 100-130 kDa as well as 60-80 kDa have been detected in Y79 cells by western blot assay.
Protocols
Product Specific Protocols | |
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WB protocol for SORCS1 antibody 18839-1-AP | Download protocol |
FC protocol for SORCS1 antibody 18839-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |