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Polycystin 1 Polyclonal antibody

Polycystin 1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 22263-1-AP

Synonyms

PBP, PC1, PKD1, Polycystin 1

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human liver tissue using Polycystin 1 Polyclonal antibody (22263-1-AP)

    IHC staining of human liver using 22263-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human liver tissue using Polycystin 1 Polyclonal antibody (22263-1-AP)

    IHC staining of human liver using 22263-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 40x lens).

  • Immunohistochemistry (IHC) staining of mouse kidney tissue using Polycystin 1 Polyclonal antibody (22263-1-AP)

    IHC staining of mouse kidney using 22263-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieved with Sodium Citrate buffer (pH 6.0).

Tested Applications

Positive IHC detected inhuman liver tissue, mouse kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

22263-1-AP targets Polycystin 1 in IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name polycystic kidney disease 1 (autosomal dominant)
Calculated Molecular Weight 463 kDa
GenBank Accession NumberNM_000296
Gene Symbol Polycystin 1/PKD1
Gene ID (NCBI) 5310
RRIDAB_2879053
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Polycystin 1 (PC1) is also named as PKD1, and Autosomal dominant polycystic kidney disease 1 protein, and belongs to the polycystin family. PKD1 and PKD2 are formed component of a heteromeric calcium-permeable ion channel. PKD1 is considered an orphan, atypical G protein coupled receptor complexed with TRPP2 (Polycystin 2 or PKD2), a Ca2+-permeable ion channel (PMID:27214281). PKD1 is involved in renal tubulogenesis (PMID:12482949).

Protocols

Product Specific Protocols
IHC protocol for Polycystin 1 antibody 22263-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols