Proenkephalin-A Polyclonal antibody

Proenkephalin-A Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 13531-1-AP

Synonyms

Opioid growth factor, PENK, proenkephalin, Proenkephalin A, Proenkephalin-A



Tested Applications

Positive IHC detected inhuman testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13531-1-AP targets Proenkephalin-A in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Proenkephalin-A fusion protein Ag4428
Full Name proenkephalin
Calculated Molecular Weight 267 aa, 31 kDa
GenBank Accession NumberBC032505
Gene Symbol Proenkephalin A
Gene ID (NCBI) 5179
RRIDAB_2161510
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Proenkephalin-A (PENK) is also named as SynenkephalinMet-enkephalin and Opioid growth factor (OGF), and belongs to the opioid neuropeptide precursor family. PENK is a neuropeptide that competes with and mimics the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (PMID:7057924). PENK hypermethylation is also associated with bladder cancer, hepatocellular carcinoma, colorectal cancer, and prostate cancer (PMID:36403035).


Protocols

Product Specific Protocols
IHC protocol for Proenkephalin-A antibody 13531-1-APDownload protocol
Standard Protocols
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