MLYCD Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 15265-1-AP

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Freight/Packing

Con: 29 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human testis tissue, human heart tissue, rat brain tissue, mouse testis tissue, HT-1080 cells, mouse heart tissue, mouse brain tissue, HepG2 cells

Positive IP detected in:
mouse heart tissue

Positive IHC detected in:
human kidney tissue, human liver tissue, human heart tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:5000
IP : 0.5-4.0 ug for IP and 1:200-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
malonyl-CoA decarboxylase

Calculated molecular weight:
55 kDa

Observed molecular weight:
50 kDa,55 kDa,66 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MLYCD

Synonyms
malonyl CoA decarboxylase, MCD, MLYCD
Background

MLYCD, also named as MCD, is a 50-55 kDa protein. It is an enzyme that catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. 66 kDa MLYCD protein has been identified in normal cell lines. Some patients give the 68-83 kDa smeary band. (PMID:12955715)


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