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ITGA6X1B Polyclonal antibody

ITGA6X1B Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 20232-1-AP

Synonyms

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of mouse heart tissue using ITGA6X1B Polyclonal antibody (20232-1-AP)

    WB analysis of mouse heart using 20232-1-AP

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 20232-1-AP (ITGA6-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of mouse kidney tissue using ITGA6X1B Polyclonal antibody (20232-1-AP)

    WB analysis of mouse kidney using 20232-1-AP

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20232-1-AP (ITGA6-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inmouse heart tissue, mouse kidney tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

20232-1-AP targets ITGA6X1B in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityrat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name integrin, alpha 6
Calculated Molecular Weight 127 kDa
Observed Molecular Weight 62 kDa
GenBank Accession NumberNM_001079818
Gene Symbol Integrin alpha 6
Gene ID (NCBI) 3655
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ITGA6, also named asITGA6B, CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. This antibody is specific to isoform Alpha-6X1X2B, isoform Alpha-6X1B and isoform Alpha-6X2B.

Publications

SpeciesApplicationTitle
ratWB,IF

J Biomech

Integrin endocytosis on elastic substrates mediates mechanosensing.

Authors - Jing Li
View Article