HEXIM1 Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 15676-1-AP

Featured Product KD/KO validated

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Con: 49 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, human brain tissue, MCF-7 cells, rat liver tissue

Positive IP detected in:
MCF-7 cells

Positive IHC detected in:
human breast cancer tissue, human cervical cancer tissue, human placenta tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
hexamethylene bis-acetamide inducible 1

Calculated molecular weight:
41 kDa

Observed molecular weight:
70, 54 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

Cardiac lineage protein 1, CLP1, EDG1, HEXIM1, HIS1, MAQ1, Menage a quatre protein 1, Protein HEXIM1

HEXIM1, also named CLP1, EDG1, HIS1 or MAQ1, is best known as the inhibitor of positive transcription elongation factor b, which regulates the transcription elongation of RNA polymerase II and controls 60-70% of mRNA synthesis. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Previous studies showed that HEXIM1 interacts with two key p53 regulators, nucleophosmin and HDM2, implying a possible connection between HEXIM1 and the p53 signaling pathway.The mainstream MW of this protein is 70 and 54 kDa. Catalog#15676-1-AP recognises both 70 and 54 kDa band.

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