HABP2 AntibodyRabbit Polyclonal
|In-house applications||ELISA, IHC Application not tested? Please see our Guarantee.|
|Published applications||Publications||0 citations –view here|
|Species specificity||Human,Mouse,Rat; other species not tested.|
|Positive IHC detected in||human liver cancer tissue|
|Recommended dilution||IHC : 1:50-1:500|
IP = Immunoprecipitation
|Source||Rabbit||Purification method||Antigen affinity purification|
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Aliquoting is unnecessary for -20oC storage
|Immunogen||HABP2 fusion protein ag3981||Full name||hyaluronan binding protein 2|
|BC031412||Gene ID (NCBI)||3026|
|Gene symbol||HABP2||Synonyms||Factor VII activating protease, FSAP, HABP, HABP2, HGFAL, hyaluronan binding protein 2, PHBP|
HABP2 is also named as HGFAL, PHBP and belongs to the peptidase S1 family. It can activate coagulation factor VII and prourokinase and release the vasoactive peptide bradykinin by cleaving kininogen and is an important role in the regulation of the haemostasis system as well as fibroproliferative inflammatory processes (PMID:21655671). HABP2 is present as the 70 kDa inactive single chain precursor in human plasma and transforms to the active two chain form, 50 kDa heavy chain and 27 kDa light chain,and the 50 kDa heavy chain changes to two 26 kDa fragments, and 27 kDa light chain to 17 kDa and 8 kDa fragments, which are all bridged by disulfide linkages, by autocleavage(PMID:11217080).