H2BFM AntibodyRabbit Polyclonal
|Species specificity||human; other species not tested.|
IP = Immunoprecipitation
|Source||Rabbit||Purification method||Antigen affinity purification|
|Isotype||IgG||Storage||PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.|
|Immunogen||Peptide||Full name||H2B histone family, member M|
|XM_936705||Gene ID (NCBI)||286436|
H2BFM belongs to the histone H2B family. H2BFM is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. H2BFM plays a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.