Histone H1.0 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 17510-1-AP

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Size: 09µ/gram

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Species specificity:
Human, Mouse, Rat

Positive WB detected in:
A431 cells, HeLa cells, Jurkat cells, mouse spleen tissue, rat spleen tissue

Positive IP detected in:
A431 cells

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:5000
IP : 1:200-1:2000
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

Immunogen Information


Full name:
H1 histone family, member 0

Calculated molecular weight:
21 kDa

Observed molecular weight:
32kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
H1F0

Synonyms
H1 histone family, member 0, H10, H1F0, H1FV, Histone H1, Histone H1(0), Histone H1.0
Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.Linker histones are involved in the formation of higher order structure in chromatin and the maintenance of overall chromatin compaction. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.Histone H1.0 (H1F0,H1FV) is a linker histone that is widely expressed in many tissues and almost all vertebrates, unlike some other linker histones. The observed molecular weight of H1F0 is about 32 kDa.


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