GABRR1 Polyclonal antibody
GABRR1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, IF, IP, CoIP, ELISA
Conjugate
Unconjugated
Cat no : 25899-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | mouse brain tissue, mouse skeletal muscle tissue |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
WB | See 2 publications below |
IF | See 1 publications below |
IP | See 1 publications below |
CoIP | See 1 publications below |
Product Information
The immunogen of 25899-1-AP is GABRR1 Fusion Protein expressed in E. coli.
Tested Reactivity | human, mouse |
Cited Reactivity | mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | GABRR1 fusion protein Ag23165 |
Full Name | gamma-aminobutyric acid (GABA) receptor, rho 1 |
Calculated Molecular Weight | 479 aa, 56 kDa |
Observed Molecular Weight | 50-56 kDa |
GenBank Accession Number | BC130344 |
Gene Symbol | GABRR1 |
Gene ID (NCBI) | 2569 |
RRID | AB_2880290 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.
Protocols
Product Specific Protocols | |
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WB protocol for GABRR1 antibody 25899-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Insect Sci Rho 1 participates in parasitoid wasp eggs maturation and host cellular immunity inhibition | ||
Biochem Biophys Res Commun Extraction method combining saponin and trehalose useful for analyzing fragile intermolecular association | ||
Transl Psychiatry Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice |