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DNAH6 Polyclonal antibody

DNAH6 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 18080-1-AP

Synonyms

Ciliary dynein heavy chain 6, DNAH6, Dnahc6, DNHL1, Dynein heavy chain 6, axonemal, HL 2, HL2, KIAA1697

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of mouse brain tissue using DNAH6 Polyclonal antibody (18080-1-AP)

    IHC staining of mouse brain using 18080-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18080-1-AP (DNAH6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human small intestine tissue using DNAH6 Polyclonal antibody (18080-1-AP)

    IHC staining of human small intestine using 18080-1-AP

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 18080-1-AP (DNAH6 antibody) at dilution of 1:200 (under 40x lens).

  • Immunohistochemistry (IHC) staining of mouse brain tissue using DNAH6 Polyclonal antibody (18080-1-AP)

    IHC staining of mouse brain using 18080-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18080-1-AP (DNAH6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human small intestine tissue using DNAH6 Polyclonal antibody (18080-1-AP)

    IHC staining of human small intestine using 18080-1-AP

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 18080-1-AP (DNAH6 antibody) at dilution of 1:200 (under 10x lens).

Tested Applications

Positive IHC detected inhuman small intestine tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IHCSee 1 publications below

Product Information

18080-1-AP targets DNAH6 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DNAH6 fusion protein Ag12774
Full Name dynein, axonemal, heavy chain 6
Calculated Molecular Weight475 kDa
GenBank Accession NumberBC104884
Gene Symbol DNAH6
Gene ID (NCBI) 1768
RRIDAB_2878493
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DNAH6(Dynein heavy chain 6, axonemal) is also named as DNAHC6, DNHL1, HL2, KIAA1697 and belongs to the dynein heavy chain family.Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains(PMID:8812413). It is a force generating protein of respiratory cilia and produces force towards the minus ends of microtubules.This antibody is specific to DNAH6.

Protocols

Product Specific Protocols
IHC protocol for DNAH6 antibody 18080-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
human,mouseIHC

Mol Psychiatry

FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors.

Authors - Minjie Shen
View Article