DNAH17 Polyclonal antibody
DNAH17 Polyclonal Antibody for WB, IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
WB, IHC, ELISA, IF
Conjugate
Unconjugated
Cat no : 24488-1-AP
Synonyms
Validation Data Gallery
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Tested Applications
| Positive WB detected in | mouse testis tissue, rat testis tissue |
| Positive IHC detected in | human kidney tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 3 publications below |
| IF | See 7 publications below |
Product Information
24488-1-AP targets DNAH17 in WB, IHC, ELISA, IF applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DNAH17 fusion protein Ag20033 |
| Full Name | dynein, axonemal, heavy chain 17 |
| Calculated Molecular Weight | 4485 aa, 512 kDa |
| Observed Molecular Weight | 500-512 kDa |
| GenBank Accession Number | BC112284 |
| Gene Symbol | DNAH17 |
| Gene ID (NCBI) | 8632 |
| RRID | AB_2879568 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for DNAH17 antibody 24488-1-AP | Download protocol |
| IHC protocol for DNAH17 antibody 24488-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Clin Genet Loss-of-function mutation in DNAH8 induces asthenoteratospermia associated with multiple morphological abnormalities of the sperm flagella. | ||
Reprod Biomed Online A novel mutation in DNAH17 is present in a patient with multiple morphological abnormalities of the flagella. | ||
J Assist Reprod Genet The effect of a novel LRRC6 mutation on the flagellar ultrastructure in a primary ciliary dyskinesia patient. | ||
Ann Hum Genet DNAH17 is associated with asthenozoospermia and multiple morphological abnormalities of sperm flagella. | ||
Hum Mol Genet Population-based genetic analysis in infertile men reveals novel mutations of ADAD family members in patients with impaired spermatogenesis | ||
Ecotoxicol Environ Saf Microcystin leucine arginine induces human sperm damage: Involvement of the Ca2+/CaMKKβ/AMPK pathway |
