C4orf14 Polyclonal antibody
C4orf14 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 20323-1-AP
Synonyms
Validation Data Gallery
Product Information
The immunogen of 20323-1-AP is C4orf14 Fusion Protein expressed in E. coli.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C4orf14 fusion protein Ag14186 |
| Full Name | chromosome 4 open reading frame 14 |
| Calculated Molecular Weight | 698 aa, 78 kDa |
| GenBank Accession Number | BC004894 |
| Gene Symbol | C4orf14 |
| Gene ID (NCBI) | 84273 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Nitric oxide associated-1 (NOA1), also known as C4orf14, is an evolutionarily conserved guanosine triphosphate (GTP) binding protein. It localizes predominantly to mitochondria in mammalian cells. Human NOA1 has been shown to interact with complex I of the electron transport chain and with three mitoribosomal proteins, MRPL12, MRPS27, and MRPS29, indicating that NOA1 may interact with the mitoribosome. Recent studies suggest that C4orf14 interacts with human mitochondrial nucleoids, and is involved in the biogenesis of the small mitochondrial ribosomal subunit.
