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BBS7 Polyclonal antibody

BBS7 Polyclonal Antibody for IF/ICC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, ELISA

Conjugate

Unconjugated

Cat no : 13458-1-AP

Synonyms

BBS2-like protein 1, BBS2L1, BBS 7, Bardet-Biedl syndrome 7 protein

Validation Data Gallery

Filter:
  • Immunofluorescence (IF) / fluorescent staining of hTERT-RPE1 cells using BBS7 Polyclonal antibody (13458-1-AP)

    IF Staining of hTERT-RPE1 cells using 13458-1-AP

    IF result (pericentriolar staining) of anti-BBS7 (13458-1-AP, 1:50) with serum-starved hTERT-RPE1 by Dr. Moshe Kim.

Tested Applications

Positive IF/ICC detected inhTERT-RPE1 cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13458-1-AP targets BBS7 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BBS7 fusion protein Ag4314
Full Name Bardet-Biedl syndrome 7
Calculated Molecular Weight 715 aa, 80 kDa
GenBank Accession NumberBC032691
Gene Symbol BBS7
Gene ID (NCBI) 55212
RRIDAB_2877952
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

BBS7, also named as BBS2L1, is a component of the BBSome complex which is required for ciliogenesis but is dispensable for centriolar satellite function. BBS7 is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome.

Publications

SpeciesApplicationTitle
mouseWB,IF

EMBO J

Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.

Authors - Shichao Duan
View Article