ADAM19 Polyclonal antibody

ADAM19 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 22216-1-AP

Synonyms

ADAM 19, ADAM19, FKSG34, MADDAM, Meltrin beta, MLTNB



Published Applications

WBSee 1 publications below

Product Information

The immunogen of 22216-1-AP is ADAM19 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ADAM19 fusion protein Ag17544
Full Name ADAM metallopeptidase domain 19 (meltrin beta)
Calculated Molecular Weight 955 aa, 105 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC024214
Gene Symbol ADAM19
Gene ID (NCBI) 8728
RRIDAB_2879034
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Meltrinβ(ADAM19) is a metalloprotease-disintegrin expressed in the peripheral nervous system and other organs during embryogenesis. Its specific patterns of expression during embryogenesis suggest that it is involved in the development of the peripheral nervous system, skeletal muscle, bone and heart tissue(PMID:12482604). It participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell.

Publications

SpeciesApplicationTitle
humanWB

Front Cell Dev Biol

Epigenetic Regulation of a Disintegrin and Metalloproteinase (ADAM) Transcription in Colorectal Cancer Cells: Involvement of β-Catenin, BRG1, and KDM4.

Authors - Lina Sun